The Bio Report
Beefing Up Computational Muscle to Understand Molecular Activity of Drug Candidates
Jan 10, 2024
Nadia Harhen, an expert in drug development, discusses the challenges in drug discovery and the potential of quantum-inspired computing. Sandbox AQ aims to accelerate drug development, reduce costs, and improve clinical success rates. The podcast also explores the history and business model of Sandbox AQ, the impact of AI in drug development, and utilizing failed clinical trial data and AI to design specialized trials.
31:45
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Quick takeaways
- Sandbox AQ is leveraging quantum-inspired computing to optimize drug development for neurodegenerative diseases and cancer, aiming to bring better leads sooner and improve the failure rate of drugs in development.
- Sandbox AQ applies AI to accelerate drug development, reducing time and cost, improving success rates, and optimizing drug properties through flexible and fast computational platforms.
Deep dives
Sandbox AQ's Approach to Drug Development and Quantum-Inspired Computing
Sandbox AQ, a company that spun out of Alphabet, is leveraging quantum-inspired computing to address the challenges of drug development for neurodegenerative diseases and cancer. By optimizing drug discovery processes, they aim to bring better leads sooner and improve the failure rate of drugs in development. Their unique approach combines physics simulations with AI to explore the chemical space and optimize drug properties. While drug discovery is their main focus, they also apply similar techniques to materials, chemistry, and finance. Their simulations utilize classical hardware and the principles of quantum physics to piece together a grounded understanding of molecular interactions.
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