Phoenix Sepsis Criteria with Dr. Nelson Sanchez-Pinto Part 2

Feb 26, 2024

Exploration of the Phoenix sepsis criteria focusing on pulmonary criteria and concerns about practice variations. Discussing Menotario pressures and lactate levels in cardiovascular dysfunction assessment. Highlighting the need for standardized sepsis criteria for localized screening based on risk factors. Implementing Phoenix criteria for sepsis screening tools and real-time surveillance of sepsis using data-driven decisions.

Ask episode

Chapters

Transcript

Episode notes

Introduction

00:00 • 4min

Exploring Menotario Pressures and Lactate Levels in Sepsis Criteria

04:27 • 5min

Defining and Tailoring Sepsis Criteria for Localized Screening

09:24 • 1min

Utilizing Phoenix Criteria for Sepsis Screening Tools

10:51 • 4min

Exploring the Computable Phenotype and Real-Time Surveillance of Sepsis

15:15 • 6min

L. Nelson Sanchez-Pinto, MD, is a Pediatric intensivist at Lurie Children’s Hospital of Chicago, where he is also an Associate Professor of Pediatrics at Northwestern University Feinberg School of Medicine.

Dr. Sanchez-Pinto co-led an international group of researchers in the Society of Critical Care Medicine Pediatric Sepsis Definition Task Force for the Development and Validation of the new Phoenix Criteria for Pediatric Sepsis and Septic Shock that was featured at the 2024 SCCM conference.

Learning Objectives:

By the end of this podcast, listeners should be able to discuss:

The limitations of prior definitions of pediatric sepsis and the rationale for creating the Phoenix Sepsis Criteria.
The methods and key outcomes used for deriving the Phoenix Sepsis Criteria.
How to diagnose sepsis using the Phoenix Sepsis Criteria.
General limitations of the Phoenix Sepsis Criteria.
Next steps in implementing the Phoenix Sepsis Criteria and the direction it provides for future research.

References:

Sanchez-Pinto LN, Bennett TD, DeWitt PE, et al. Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. JAMA. Published online January 21, 2024. doi:10.1001/jama.2024.0196

Schlapbach LJ, Watson RS, Sorce LR, Argent AC, Menon K, Hall MW, Akech S, Albers DJ, Alpern ER, Balamuth F, Bembea M, Biban P, Carrol ED, Chiotos K, Chisti MJ, DeWitt PE, Evans I, Flauzino de Oliveira C, Horvat CM, Inwald D, Ishimine P, Jaramillo-Bustamante JC, Levin M, Lodha R, Martin B, Nadel S, Nakagawa S, Peters MJ, Randolph AG, Ranjit S, Rebull MN, Russell S, Scott HF, de Souza DC, Tissieres P, Weiss SL, Wiens MO, Wynn JL, Kissoon N, Zimmerman JJ, Sanchez-Pinto LN, Bennett TD; Society of Critical Care Medicine Pediatric Sepsis Definition Task Force. International Consensus Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024 Jan 21. doi: 10.1001/jama.2024.0179. Epub ahead of print. PMID: 38245889.

Richesson RL, Smerek MM, Blake Cameron C. A Framework to Support the Sharing and Reuse of Computable Phenotype Definitions Across Health Care Delivery and Clinical Research Applications. EGEMS (Wash DC). 2016 Jul 5;4(3):1232. doi: 10.13063/2327-9214.1232. PMID: 27563686; PMCID: PMC4975566.

Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & Zac

Support the show

How to support PedsCrit:
Please complete our Listener Feedback Survey
Please rate and review on Spotify and Apple Podcasts!
Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.

Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.