Understanding the kidneys' role in the body’s balance is essential for the MCAT and beyond.

In this episode, host Sam Smith discusses renal physiology, covering everything from kidney anatomy to the nephron’s critical functions in filtration, reabsorption, secretion, and excretion. You’ll explore the roles of the renal cortex and medulla, learn about the loop of Henle, and uncover the importance of ions, plasma volume, and pH regulation in kidney function. Plus, we’ll examine hormones like ADH and aldosterone and their impact on fluid balance, as well as essential measurements like glomerular filtration rate (GFR) for assessing kidney health.

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Jump into the conversation:

(00:00) Intro to renal physiology

(02:43) Kidney anatomy overview

(08:38) Nephron structure and function

(09:50) Six key functions of the kidney

(12:03) Nephron Processes: Filtration

(17:32) Nephron Processes: Reabsorption and secretion

(22:51) The Loop of Henle

(26:05) Understanding osmolarity in the Loop of Henle

(26:55) Ion transport in the ascending limb

(32:04) The role of the collecting duct

(37:18) Hormonal regulation of the nephron

(46:50) Key measurements of renal function

(50:15) MCAT Advice of the Day

Renal Physiology