Understanding Measurable Residual Disease in CLL

Measurable Residual Disease (MRD) in Chronic Lymphocytic Leukemia (CLL) refers to cancer cells that were previously undetectable but can now be seen using advanced techniques like flow cytometry and next-generation sequencing. Achieving undetectable MRD levels may indicate a deeper remission, potentially leading to better outcomes. While the importance of MRD in CLL treatment is debated due to the indolent nature of the disease, eradicating even the last cancer cell could theoretically result in a cure.