Explore the history of mammography, from the discovery of X-rays to early advancements in breast imaging. Learn about the significance of mammography in breast cancer treatment and monitoring. Discover the pioneers and advocacy for screening mammograms in the 1950s. Understand the impact of mammography on early detection of breast cancer and the evolution of mammography technology. Also, a chapter about Assassin's Creed Discovery Tours and their educational applications.
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Quick takeaways
The discovery of X-rays in 1895 laid the foundation for the development of mammography, enabling the detection and diagnosis of breast cancer through imaging.
Advancements in mammography technology, such as breast compression and digital imaging, have improved the accuracy and detail of mammograms.
Deep dives
Origin and Discovery of X-Rays
The history of mammography begins with the discovery of X-rays by Wilhelm Conrad Rontkin in 1895. While experimenting with a crooks tube, Rontkin accidentally discovered a form of radiation that could pass through various substances, including the human body, and create images on photographic plates. This discovery laid the foundation for the development of mammography and its use in detecting and diagnosing breast cancer.
Early Use of X-Rays in Breast Imaging
In the early 20th century, researchers started exploring the use of X-rays for imaging breast tissue. Albert Solomon in Berlin was the first person known to have X-rayed breast tissue in 1913. This pioneering work led to the recognition that breast cancer could be detected and localized through mammograms, despite the limitations of X-ray imaging at the time. Other researchers, such as Otto Kleinschmidt and Stafford Leak Warren, further advanced the technique and developed methods for positioning the breast and obtaining clearer images.
Advancements in Mammography Technology
In the 1950s and 1960s, advancements in mammography technology led to the development of dedicated equipment specifically designed for breast imaging. Raul Lebourn introduced breast compression, which improved image clarity and the ability to distinguish between cancerous and benign masses. Robert Egan, Jacob Gershon Cohen, and Helen Ingleby conducted research that supported the use of mammography as a screening tool, detecting early-stage breast cancer in asymptomatic individuals. Over the years, digital mammography and 3D digital mammography have been introduced, providing more accurate and detailed images.
Debates and Controversies
The efficacy of mammography as a screening tool and the optimal age to start screening have been subjects of ongoing debates and controversies. Critics raise concerns about false positives, overdiagnosis, and overtreatment, especially in younger individuals. There are also disparities in access to mammograms, leading to inequalities in breast cancer detection rates and survival rates, particularly among minority and low-income populations. Ongoing research and advancements in technology aim to address these concerns and improve the effectiveness of mammography screening.
The history of mammography begins with the discovery of X-rays in 1895. But it took a very long time for breast imaging to advance, in part because it wasn't prioritized.
Research:
“The St George’s Four: Meet the women that shaped St George’s.” St. George’s University of London. 3/8/2019. https://www.sgul.ac.uk/news/the-st-george-s-four-meet-the-women-that-shaped-st-george-s
American Physical Society. “This Month in Physics History.” November 2001 (Volume 10, Number 10). https://www.aps.org/publications/apsnews/200111/history.cfm
Bassett, Lawrence W. and Richard H. Gold. “The Evolution of Mammography.” AJR 150:493-498, March 1988.
Bhidé, Amar et al. “Case Histories of Significant Medical Advances: Mammography.” Harvard Business School Working Paper 20-002. 2021.
CROWTHER, J. Röntgen Centenary and Fifty Years of X-Rays. Nature 155, 351–353 (1945). https://doi.org/10.1038/155351a0
Davis, Devra. “The Secret History Of Mammography.” HuffPost. 11/17/2011. https://www.huffpost.com/entry/the-secret-history-of-mam_b_364733
Haus, Arthur G. “Historical Technical Developments in Mammography. Technology in Cancer Research & Treatment. ISSN 1533-0346. Volume 1, Number 2, April (2002)
Kalaf, José Michael. “Mammography: a history of success and scientific enthusiasm.” Radiol Bras. 2014 Jul/Ago;47(4):VII–VIII. http://dx.doi.org/10.1590/0100-3984.2014.47.4e2
Lerner, Barron H. “’To See Today With the Eyes of Tomorrow: A History of Screening Mammography.’” CBMH/BCMH I Volume 20:2 2003 / p. 299-321.
Lerner, Barron H. “Why Was the US Preventive Services Task Force’s 2009 Breast Cancer Screening Recommendation So Objectionable? A Historical Analysis.” The Milbank Quarterly, September 2022, Vol. 100, No. 3 (September 2022). https://www.jstor.org/stable/10.2307/48713998
Lienhard, Dina A., "Mammography". Embryo Project Encyclopedia ( 2018-03-25 ). ISSN: 1940-5030 https://hdl.handle.net/10776/13056
Mao X, He W, Humphreys K, et al. Breast Cancer Incidence After a False-Positive Mammography Result. JAMA Oncol. Published online November 02, 2023. doi:10.1001/jamaoncol.2023.4519
Mekasut, Nitida. “Mammography: From Past to Present.” The Bangkok Medical Journal. February 2011. https://www.bangkokmedjournal.com/sites/default/files/fullpapers/2010-1-Mekasut.pdf
Nicosia, Luca et al. “History of Mammography: Analysis of Breast Imaging Diagnostic Achievements over the Last Century.” Healthcare 2023, 11, 1596. https://doi.org/10.3390/healthcare11111596
Ritvo, Max. "The Role of Diagnostic Roentgenology in Medicine." New England Journal of Medicine 262, no. 24 (1960): 1201-09.
Skloot, Rebecca. “Taboo Organ: How a Pitt Alum Refused to Let Mammography Be Ignored.” Pittmed. April 2001. https://www.pittmed.health.pitt.edu/apr_2001/taboo_organ.pdf
Warren, Stafford L. “A Roentgenologic Study of the Breast.” The American Journal of Roentgenology and Radium Therapy 1930-08: Vol 24 Iss 2.
Zenger, Ingo. “The history of mammography.” Siemens. https://www.medmuseum.siemens-healthineers.com/en/stories-from-the-museum/history-mammography