Neurology Minute

Body-First Lewy Body Disease Observed in Postmortem Tissue from Prediagnostic Individuals - Part 1

May 16, 2025
Dr. Jeff Ratliff and Dr. Per Borghammer delve into the intriguing world of Lewy Body Disease. They contrast the body-first and brain-first models, shedding light on how these theories affect symptoms and disease progression. The discussion uncovers vital insights into postmortem tissue research from individuals before diagnosis, revealing the complexities of this condition. Tune in for a fascinating exploration of neurological pathology and its implications for understanding Lewy Body Disease!
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INSIGHT

Brain-First vs Body-First Lewy Disease

  • Lewy-Body disease progresses via two main subtypes: brain-first and body-first.
  • Brain-first starts from the brain (olfactory bulb), body-first starts from peripheral organs like the gut.
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