

Season 3 - Ep.12: Extended interview on the relevance and management of ventricular ectopic beats
Mar 27, 2025
In this enlightening conversation, Professor Thomas Deneke, a leading expert in ventricular ectopy, shares his insights on managing ventricular ectopic beats. He discusses the critical connection between left ventricular function and premature ventricular contractions, stressing the importance of monitoring these beats in patients with heart conditions. Deneke also explores treatment options, including the role of exercise testing, beta blockers, and catheter ablation, especially for those recovering from heart attacks, emphasizing personalized care for optimal outcomes.
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PVC Burden and LV Dysfunction
- There's no clear PVC burden cutoff for intervention, but higher burdens increase the risk of left ventricular (LV) dysfunction.
- Daily PVC burden varies; monomorphic PVCs differ from polymorphic PVCs, which often indicate underlying heart disease.
Stress Testing for PVCs
- Use stress testing to assess PVCs. Benign PVCs decrease during stress, while increased PVCs suggest ischemia or higher cardiac event risk.
Medical Therapy for PVCs
- Beta-blockers are generally preferred for patients with structural heart disease and PVCs or non-alpha PVCs without structural disease.
- Catheter ablation is increasingly used due to its higher efficacy and lower complication rates compared to medication.