In September, former England rugby captain Lewis Moody received a devastating diagnosis that changed his life forever.
The 47-year-old Rugby World Cup winner is the latest retired professional player to be told he has the fatal muscle-wasting condition motor neurone disease.
What do we know about the possible causes of MND? Is there a link between extreme exercise and developing the disease? And are we any closer to a cure?
Niall is joined by Moody’s World Cup-winning team-mate Will Greenwood and Dr Mike Rogers, director of research and innovation at the MND Association.
Producer: Tom Gillespie and Emily Hulme
Editor: Mike Bovill