The St.Emlyn’s Podcast

Ep 290 - Shock with Rich Carden at Trauma 2030

Apr 11, 2026
Rich Carden, an intensive care trainee and trauma sciences PhD with emergency medicine roots, explains shock as cellular oxygen delivery and use. Short segments cover pressure versus perfusion, the “dose” of shock, transitions from hemorrhage to inflammatory and septic states, the glycocalyx’s role, risks of early vasopressors in an underfilled system, and why flawless basics matter.
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INSIGHT

Shock Is A Cellular Oxygen Problem

  • Shock is fundamentally inadequate delivery and utilization of oxygen at a cellular level.
  • Rich Carden explains this unifies diverse shock causes and shifts focus from blood pressure to cellular oxygenation.
INSIGHT

Pressure Is Not The Same As Perfusion

  • Blood pressure is a convenient surrogate for perfusion but not the same as flow to tissues.
  • Iain Beardsell and Rich Carden discuss pressure = heart rate × stroke volume × total peripheral resistance and its limits.
INSIGHT

Shock Phenotypes Change Over Time

  • Trauma patients progress through phases: initial hemorrhage can switch to inflammatory, vasoplegic or septic phenotypes.
  • Rich Carden highlights these phenotype switches happen on a timeline after bleeding stops.
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