

Methylene Blue: A New Hope for Cancer Treatment?
Apr 19, 2025
Methylene blue is stirring excitement for its ability to shrink tumors and slow cancer growth by disrupting cancer cell energy production. Photodynamic therapy utilizing this compound selectively destroys cancer cells while sparing healthy tissue, presenting a precise treatment option. Research shows it can shift ovarian tumors away from their preferred energy source. Unlike traditional chemotherapy, methylene blue shows minimal side effects, making it ideal for drug-resistant cancers. Proper dosing is crucial for maximizing its benefits without toxicity.
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Targeted Tumor Attack via Light
- Methylene blue activated by 630-680 nm light generates reactive oxygen species targeting cancer cells.
- It selectively accumulates in tumors, sparing healthy tissue, leading to fewer side effects than chemo.
Metabolic Disruption in Cancer
- Cancer cells rely on glucose fermentation even with oxygen (Warburg effect) for rapid growth.
- Methylene blue disrupts this metabolism, forcing cells to use oxygen-based energy, stressing and slowing tumor growth.
Study on Drug-Resistant Ovarian Cancer
- A study with carboplatin-resistant ovarian cancer implanted in mice showed tumor growth slowed with methylene blue.
- This suggests potential for patients resistant to traditional chemotherapy methods.