Stuff You Should Know

The Mystery of the Sleepy Sickness

53 snips
Oct 2, 2025
Travel back to the early 1900s and explore the enigmatic sleepy sickness, a pandemic that left patients in a deep, semi-aware state. Discover the peculiar symptoms, including hypersomnolence and catatonia, and the exploration of the illness by Dr. Constantin von Economo. Learn about the chilling connection between the outbreak and long-term Parkinsonism, as well as Oliver Sacks' groundbreaking work on revival treatments. Delve into the mysterious disappearance of the disease and current theories regarding its origins!
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INSIGHT

Sudden Global Neurological Pandemic

  • Encephalitis lethargica erupted around 1916 with sudden neurological collapse and hypersomnolence across continents.
  • It killed many, left survivors with chronic disability, and baffled contemporaneous medicine.
INSIGHT

Von Economo's Classification Breakthrough

  • Von Economo distinguished EL from other disorders and proposed an infectious origin.
  • He catalogued varied presentations, pushing the field toward epidemic investigation.
INSIGHT

Sleep Is Not Sleep In EL

  • Hypersomnolence in EL is unlike normal sleep: patients stay semi-aware but cannot control falling asleep.
  • Patients could freeze mid-action and remain unresponsive for varying durations.
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