Gianluca De Novi, founder and CEO of Circular Protocol, a Massachusetts-based layer one blockchain built on a proof of reputation consensus mechanism joins host, Ray Dogum. Circular is designed to help partners accelerate innovation in healthcare and decentralized science (DeSci) through secure, reputation-driven infrastructure.
Gianluca is a hands-on engineering executive and educator with a background in medical simulation research at Harvard, where he led groundbreaking work at the intersection of AI, blockchain, and virtual reality. Originally from Italy, he shares his personal journey to the U.S. and how a life-changing experience shifted his focus to healthcare innovation.
In the conversation, we explore the creation and purpose of Circular Protocol, its alignment with regulatory frameworks, and its potential for collaboration with government agencies. Gianluca unpacks key concepts like decentralized data integrity, ownership, and governance, and offers his perspective on blockchain as a social revolution. We also touch on the convergence of AI and blockchain, the implications of decentralized tech in healthcare, and his reflections on the singularity and future of innovation.
Guest Resources

Timestamps:

00:00 Intro

01:17 Meet Gianluca De Novi, PhD

01:56 Journey into Healthcare and Technology

04:09 Blockchain and Healthcare: A New Paradigm

05:58 Circular Protocol: Structure and Vision

07:22 Decentralization and Social Innovation

12:19 Technical Aspects of Circular Protocol

17:24 Proof of Reputation Consensus Mechanism

22:19 The Role of Education in Healthcare Innovation

25:26 The Importance of Data Auditing in AI Systems

25:59 Blockchain as a Solution for Data Certification

27:34 Real-World Applications of Blockchain in Healthcare

28:44 Developer Onboarding

29:28 Data Privacy and Decentralization

33:04 Challenges in Blockchain Adoption

34:22 Circular's Protocol Roadmap

36:14 Personal Insights and Influences

40:37 Philosophical Thoughts on AI Singularity

45:04 Future Outlook

Health Unchained Links

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Ep. 131: Rebuilding Trust in Healthcare - Gianluca De Novi, PhD (CEO Circular Protocol)