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ESC TV Today – Your Cardiovascular News
Season 2 - Ep. 22: Lipid-lowering therapy beyond statins - Management of cardiac fibroelastoma
Aug 15, 2024
Join experts Stephan Achenbach, a leading cardiology figure, Carlos Aguiar, lipid management authority, Kyle Klarich, cardiac specialist, and Konstantinos Koskinas, renowned researcher, as they dive into innovative strategies for managing cardiac fibroelastomas and advancing lipid therapy beyond statins. They discuss the latest research highlighting new therapeutic options, evaluate the effectiveness and side effects of current treatments, and examine the importance of LDL cholesterol reduction in cardiovascular health. A must-listen for those in the field!
21:15
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Quick takeaways
- Lipid management strategies are increasingly incorporating therapies beyond statins, including ezetimibe and newer options like PCSK9 inhibitors, to better meet LDL targets.
- Early-stage hypertrophic cardiomyopathy patients demonstrated improved physical quality of life with valsartan, signifying the importance of tailored treatment approaches in this population.
Deep dives
Sex Differences in Familial Hypercholesterolemia
Men with familial hypercholesterolemia experience significantly higher risks and burdens of atherosclerotic cardiovascular disease compared to women. An analysis from the Safe Heart study demonstrated that the prevalence of cardiovascular disease was nearly three times greater in males at enrollment, primarily due to coronary artery disease. Over a median follow-up of a decade, males had a 90% higher incidence of atherosclerotic events and were 70% more likely to die from cardiovascular causes, despite similar reductions in LDL cholesterol between the sexes. This suggests that healthcare strategies should account for these sex differences in risk prediction and management of familial hypercholesterolemia.
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Discover
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Listen to the best highlights from the podcasts you love and dive into the full episode