The Second Opium War (1856-1860) lead to the opening of Danshui, near Taipei, and Anping (Tainan) as treaty ports. Soon after, the Qing authorities opened Takao (Kaohsiung) and Keelung to foreign ships. First came the foreign traders, then the missionaries... one of the latter would become a household name on the island: George Leslie Mackay, a man who used his dentistry skills -- and a pair of pliers -- to help spread the word.
The Taiwan History Podcast: Formosa Files