This Week in Cardiology May 09 2025 This Week in Cardiology
May 9, 2025
The podcast dives into the controversial KETO-CTA study, exploring its impact on cholesterol and plaque progression. It examines subclinical atrial fibrillation and the questions surrounding the need for anticoagulation treatment. Additionally, there’s an exciting discussion on the ESSENCE trial, highlighting the potential benefits of GLP-1 agonists for fatty liver disease, suggesting significant implications for cardiology. The balance between lifestyle changes and treatment strategies for cardiovascular care is also scrutinized, inviting a thoughtful dialogue.
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Prefer Balanced Over Keto Diets
- Despite public enthusiasm, extremely high LDL from keto diets is concerning and lacks strong evidence for safety.
- Balanced diets like the Mediterranean diet are recommended over keto for heart health.
Subclinical AF Anticoagulation Advice
- Anticoagulation in subclinical atrial fibrillation offers minimal net benefit due to low stroke risk and increased bleeding.
- Treatment decisions should align with patient preferences given the uncertain benefit.
Markov Model on AF Treatment
- A Markov model estimated that oral anticoagulants in subclinical AF yield only about one additional quality-adjusted week of life over 10 years.
- Stroke reduction benefits closely offset by increased bleeding risks.