In this special episode on Low and No Calorie Sweeteners, our host, Dr. Neil Skolnik will take a deep dive into the randomized evidence about the efficacy of Low and No Calorie Sweeteners. Also discussed will be observational trials on NNS, as well as safety. Finally, there will be a discussion of the World Health Organization recommendations on Nonnutritive sweeteners as well as practical clinical insights.

This special episode is supported by an independent educational grant from Heartland Food Group, the maker of the Splenda Group of Products. For more information just go to: www.splenda.com .

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Kathrine Appleton, PhD, Professor of Psychology, Bournemouth University.

Articles discussed:

The effects of low-calorie sweeteners on energy intake and body weight: a systematic review and meta-analyses of sustained intervention studies. Int J Obes (Lond). 2021 Mar;45(3):464-478

Use of non-sugar sweeteners: WHO guideline

Non-nutritive sweeteners and their impacts on the gut microbiome and host physiology. Front Nutr.2022;9:988144

Diabetes Core Update Special Edition Non-Nutritive Sweeteners Final