Nitazenes and the Consequences of Drug Prohibition
Jan 9, 2024
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The podcast explores the emergence of nitazenes, a highly potent synthetic opioid, and the rise in nitazene overdoses. It discusses the need for a shift in drug policy towards legalization and harm reduction, as well as the consequences of drug prohibition and the need for state intervention in overdose prevention.
Nitazenes, a potent category of synthetic opioids, are increasingly being used by non-medical users, leading to concerns over overdose deaths.
Instead of immediately legalizing drugs, focus should be on harm reduction strategies such as overdose prevention centers, syringe services programs, and improving access to addiction treatment.
Deep dives
Understanding Opiates and Opioids
Opiates are the natural derivative of the opium poppy, while opioids are chemically modified opiates. Opiates include morphine and coding, derived directly from the poppy. Opioids like oxycodone, hydrocodone, and fentanyl have been chemically modified to enhance certain features. Nidoxines, including isotognidoxine, are a powerful category of synthetic opioids.
The Threat of Nidoxines
Nidoxines, originally developed by a pharmaceutical company in the 1950s, are about 20 times more potent than fentanyl. Their usage by non-medical users has been increasing, causing concern. Detection of nidoxine has risen significantly, making it a potential crisis. Reports from the UK indicate its prevalence, with cases of overdose deaths caused by the mixing of nidoxines and benzodiazepines.
Addressing the Drug Problem
Opponents of drug prohibition suggest ending the prohibition and legalizing drugs. However, realistically, this may not be immediately feasible. Therefore, the focus should be on harm reduction strategies. Measures like overdose prevention centers, syringe services programs, and improving access to addiction treatment can help reduce the risks associated with drug use. Federal and state legal obstacles should be removed to facilitate harm reduction efforts.