
Relentless #36 - Max Marchione, Co-Founder of Superpower
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Aug 14, 2025 Max Marchione, co-founder of Superpower, is at the forefront of a data-driven healthcare revolution, focusing on omics and wearables. He delves into his self-experimentation journey, comparing it with empirical data approaches. Listeners will be fascinated by his insights on biohacking routines, cognitive supplements, and the future of AI in personalized health. Max also shares his ambitious visions for startup success and innovative pricing strategies to enhance product design, all while navigating the complexities of the healthcare system.
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Weekend Biohacking Rituals
- Max Marchione describes injecting thymosin alpha-1, NAD+, and retatratide during a team "Friday breakfast" ritual.
- He says thymus nalpha1 stopped a severe sore throat within 36 hours and retatratide is a GLP triple-agonist that boosts metabolism with few side effects.
Subjective Data Still Matters
- Max treats many fringe practices as early signals that later become mainstream, citing sleep trackers and CGMs.
- He balances subjective feeling with data because current measurement can't capture everything.
Simple Morning Rituals To Boost Energy
- Start mornings with simple physical hacks: jump, tongue-scrape and oil-pull to raise energy and oral health.
- Brew precise low-temperature green tea and take a high-quality multivitamin with correct cofactors and dosing.
