Locked On 49ers - Daily Podcast On The San Francisco 49ers 49ers Keys to Victory vs the Carolina Panthers on Monday Night Football
Nov 21, 2025
The discussion centers on the 49ers' game plan against the Panthers, including a deep dive into rookie Tetairoa McMillan's rising threat. There’s a debate on how best to defend against him, especially in the red zone. Ricky Pearsall's role is also highlighted as he returns to the lineup. The hosts emphasize the importance of a strong run game with McCaffrey to bolster the defense. Plus, questions arise about the 49ers' kicking situation and their ability to handle close matchups.
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Rising Rookie Threat
- Tedaroa McMillan has quickly become a true number-one receiver with size, athleticism, and surprising route-running.
- His emergence simplifies Bryce Young's transition and makes him a focal point for opposing game plans.
Limit McMillan With Bracketing
- Bracket or 'put a cap on' McMillan to limit his big-play upside, using extra defenders or over-the-top help.
- Match personnel (e.g., bigger corners or safeties) to avoid one-on-one mismatches in the red zone.
Matchup Discrepancy Looms Large
- Upton Stout's size mismatch versus McMillan (5'8.5" vs 6'5") is an exploitable target for Carolina.
- Opponents will likely scheme to force that mismatch or use slot moves to put smaller corners on McMillan.