TWiV 1040: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin discusses the public health significance of finding autochthonous melioidosis cases in the continental United States, human neural larva migrans caused by Ophidascaris robertsi ascarid, Project nextgen awards over $1.4 billion to develop the future of COVID-19 vaccines and therapeutics, excess all-cause mortality in China after ending the zero COVID policy, international pediatric COVID-19 severity over the course of the pandemic, differences in SARS-CoV-2 specific humoral and cellular immune responses after contralateral and ipsilateral COVID-19 vaccination, Pfizer and BioNTech receive positive CHMP opinion for Omicron XBB.1.5-adapted COVID-19 vaccine in the European Union, clinical antiviral efficacy of Remdesivir in COVID-19, optimal duration of systemic corticosteroids in COVID-19 treatment, clinical outcomes associated with overestimation of oxygen saturation by pulse oximetry in patients hospitalized with COVID-19, risk of autoimmune diseases following COVID-19 and the potential protective effect from vaccination.

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Links for this episode

• Public health significance of finding autochthonous melioidosis cases (PLOS)
• Human neural larva migrans caused by Ophidascaris robertsi ascarid (EID)
• Project nextgen awards over $1.4 billion to develop the future of COVID-19 vaccines and therapeutics (HHS)
• Excess all-cause mortality in China after ending the zero COVID policy (JAMA)
• International pediatric COVID-19 severity over the course of the pandemic (JAMA)
• Differences in SARS-CoV-2 specific humoral and cellular immune responses after COVID-19 vaccination (eBioMedicine)
• Pfizer/BioNTech receive positive CHMP opinion for COVID-19 vaccine in the EU (Pfizer)
• Clinical antiviral efficacy of Remdesivir in COVID-19 (JID)
• Optimal duration of systemic corticosteroids in COVID-19 treatment (OFID)
• Clinical outcomes associated with overestimation of oxygen saturation in patients with COVID-19 (JAMA)
• Risk of autoimmune diseases following COVID-19 and the potential protective effect from vaccination (eClinicalMedicine)
• Contribute to our Floating Doctors fundraiser at PWB
• Letters read on TWiV 1040
• Dr. Griffin’s COVID treatment summary (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv