35. Guideline for Vaccinations in Patients with Rheumatic and Musculoskeletal Diseases
Aug 16, 2022
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Listen in as Dr. Anne Bass discusses important guidelines for vaccinations in patients with rheumatic and musculoskeletal diseases, including the impact of certain medications like rituximab and methotrexate, navigating insurance companies using the guidelines, and highlights of the vaccination recommendations. Learn about the complexities of vaccinating pediatric patients with rheumatic diseases, optimizing vaccination strategies, new conjugate vaccines, vaccine safety, and maximizing immune responses in individuals with compromised immune systems.
Rheumatic disease patients face higher risks of under-vaccination, emphasizing the importance of vaccination guidelines.
Medications like rituximab and methotrexate impact vaccination responses, requiring specific timing adjustments for optimal immunity.
Deep dives
Vaccination Challenges for Patients with Rheumatic Diseases
Patients with rheumatic diseases face increased risks of vaccine-preventable diseases but are often under-vaccinated. Concerns exist regarding possible disease flares after vaccination and achieving immunity in immunosuppressed patients.
ACR's Comprehensive Guidelines on Vaccination
The American College of Rheumatology released the 2022 vaccination guidelines covering both pediatric and adult populations, recognizing shared medication use and issues across different diseases.
Influenza Vaccine Recommendations and Considerations
Influenza vaccine is crucial for everyone, especially those on immunosuppression. Recommendations suggest the importance of timely administration, regardless of disease activity.
Medication Adjustments and Vaccine Timing
Holding methotrexate for two weeks after influenza vaccination is recommended, while other medications like TNF inhibitors should not be altered for most vaccines. Rituximab impacts responses to various vaccines and should be considered for timing adjustments.
In this week’s episode, we discuss the "ACR’s 2022 Guideline Summary for Vaccinations in Patients with Rheumatic and Musculoskeletal Diseases" with lead author Dr. Anne Bass, Attending Physician in the Division of Rheumatology at Hospital for Special Surgery and a Professor of Clinical Medicine at Weill Cornell Medicine. During our conversation we consider the importance of guidelines for vaccines, the impact certain drugs like rituximab and methotrexate have on vaccinations, cover some vaccine highlights within the guidelines, how these guidelines can aid in navigation with insurance companies and much, much more.
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