Episode 553: MJA Podcasts 2024 Episode 12: developments in treating kidney disease, with Professor Gopi Rangan
Apr 14, 2024
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Professor Gopi Rangan, a nephrologist, discusses treating kidney disease, advice for GPs, patient support, and his busy specialist life. Topics cover managing kidney disease in vulnerable groups, Polycystic Kidney Disease, new medications like SGLT2 inhibitors, and balancing a military reservist role.
Early identification through proactive screening is crucial for managing chronic kidney disease.
New drug therapies like SGLT2 inhibitors provide promising avenues for slowing disease progression in kidney disease.
Deep dives
Prevalence and Risk Factors of Kidney Disease in Australia
Chronic kidney disease is a prevalent health issue in Australia, affecting approximately 6 million adults, with 2 million living with the condition. Early identification is crucial as kidney function can decline significantly before symptoms manifest. Risk groups include those with cardiovascular disease, diabetes, metabolic syndrome, First Australians, and certain racial groups, emphasizing the importance of proactive screening.
Challenges Faced by General Practitioners in Identifying Kidney Disease
The silent nature of kidney disease poses challenges for general practitioners in early recognition. Screening methods such as blood pressure measurement, urine analysis for proteinuria or hematuria, and blood tests for creatinine levels are essential. Recognizing risk factors and encouraging patients to seek early medical attention are critical in preventing late-stage kidney disease symptoms.
Advancements in Treating Polycystic Kidney Disease and Emerging Treatments
Polycystic Kidney Disease (PKD), a prevalent genetic condition affecting 20,000 Australians, showcases the importance of early detection and intervention. New drug therapies like SGLT2 inhibitors and mineralocorticoid receptor antagonists show promise in slowing disease progression. The availability of disease-modifying drugs like tolvaptan for PKD and updated treatment guidelines offer new avenues for managing kidney disease and improving patient outcomes.
Today we discuss developments in treating kidney disease, including advice for general practitioners, how patients can get support – and balancing life as a specialist.
My special guest is Professor Gopi Rangan, a nephrologist staff specialist at Westmead Hospital and a clinician scientist at the Westmead Institute for Medical Research.