The Intern At Work: Internal Medicine

206. Conquering Consumption: An Approach to Tuberculosis

9 snips
Sep 10, 2023
Kevin Zhang, an Internal Medicine Resident and advocate for effective tuberculosis management, dives deep into the world of TB infection and disease. He breaks down the pathophysiology of tuberculosis, revealing how it spreads and affects the body. Listeners gain insights into the latest Canadian guidelines and diagnostic methods, including the significance of patient history. Zhang also discusses tailored strategies for both latent and active TB, providing a comprehensive overview to help combat this infectious disease.
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INSIGHT

TB's Stealthy Survival Mechanism

  • Mycobacterium tuberculosis evades the immune system using mycolic acid and grows very slowly compared to typical bacteria.
  • Latent TB involves dormant bacteria within immune granulomas, asymptomatic and non-transmissible.
ADVICE

Assess TB Risk and Symptoms

  • Screen patients' social history thoroughly for TB risk factors like exposure and living conditions.
  • Ask about chronic respiratory and constitutional symptoms for TB disease suspicion.
ADVICE

Comprehensive TB Physical Exam

  • Conduct thorough physical exams focusing on cachexia, lymphadenopathy, lung auscultation, and search for extra-pulmonary signs.
  • Remember TB can affect almost any organ, so tailor exam accordingly.
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