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The Drug Discovery World Podcast
Unlock the potential of complex human liver data
Feb 21, 2024
In this podcast, Quin Wills from Ochre Bio discusses using AI to unlock the potential of complex human liver data. They are building components of the liver from scratch to study metabolic, cell death, inflammation, fibrosis, and neoplastic processes. The aim is to conduct 'clinical trials' before actual clinical trials, with a focus on enhancing success rates with modalities like SIRNA and addressing urgent global liver disease concerns.
15:50
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Quick takeaways
- OkraBio focuses on 'bottom up' human liver models to study metabolic processes in liver diseases.
- OkraBio utilizes AI to enhance scalability and complexity of human liver models for innovative discoveries.
Deep dives
OkraBio's Approach to Liver Disease Research and Development
OkraBio aims to improve three crucial aspects in chronic liver disease research: discovery, validation, and clinical trials. By leveraging advanced genetic sequencing and imaging technologies, the company generates comprehensive datasets to drive discovery. Furthermore, OkraBio focuses on human-specific validation methods, from primary human cells to whole organ testing, ensuring rigorous research standards. The company's emphasis on high success modalities like SIRNA showcases a forward-looking approach to enhancing clinical trial efficiency.
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Discover
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Listen to the best highlights from the podcasts you love and dive into the full episode