Chapter 40 - The Full Bird and Fumar de Cystica - an EM guide to the gallbladder
Feb 1, 2025
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Dr. Henry Schiller, a Mayo Clinic Professor of Surgery and Army Reserve Lieutenant Colonel, shares his expertise on gallbladder health. He discusses the formation of gallstones and the significance of timely diagnosis. The conversation delves into differentiating gallstones from cholecystitis, highlighting critical imaging techniques like ultrasound and CT scans. Insights into interpreting liver function tests and the complexity of acalculous cholecystitis are explored, along with engaging personal anecdotes from his medical journey.
Understanding the distinction between cholelithiasis and cholecystitis is crucial for timely diagnosis and management of gallbladder diseases.
The impact of diet, particularly a high-fat American diet, significantly influences gallstone formation and associated complications.
Timely surgical intervention within 24 hours of acute cholecystitis presentation is essential to minimize morbidity and prevent further complications.
Deep dives
Introduction of Dr. Henry Schiller
Dr. Henry Schiller, a distinguished figure in emergency medicine, has extensive experience in trauma and general surgery. He has been recognized multiple times for his teaching excellence and has contributed significantly to the medical literature. His background includes combat medical experience with the U.S. Army and a leadership role at the Mayo Clinic Trauma Center. The discussion highlights the value of physician education and mentorship in shaping the careers of medical professionals.
Understanding Gallbladder Terminology and Pathology
The podcast elucidates essential gallbladder terminology, including cholelithiasis and cholecystitis, to clarify the differences between conditions associated with gallstones. A key point is that gallstones can form due to lithogenic bile, which is characterized by imbalances in bile composition. The discussion emphasizes the impact of diet on gallstone formation, particularly how a high-fat American diet can contribute to increased risk. Additionally, the distinction between biliary colic—a symptom of gallstones—and acute cholecystitis emphasizes the importance of timely diagnosis and treatment to prevent complications.
Pathophysiology of Cholecystitis
Cholecystitis is described as a complex condition where irritation due to gallstones leads to inflammation of the gallbladder. The discussion outlines how increased intraluminal pressure and decreased blood flow can lead to ischemia within the gallbladder wall, creating a positive feedback loop of inflammation and infection. It is crucial to recognize the signs of cholecystitis early, as delayed treatment can significantly increase the risk of complications and the need for more invasive procedures. Understanding symptoms, such as right upper quadrant pain and the Murphy sign, is essential for appropriate clinical assessment.
Imaging and Diagnosis of Gallbladder Issues
Various imaging modalities, primarily ultrasound and CT scans, are explored for diagnosing gallbladder-related diseases. Ultrasound is highlighted as the preferred initial imaging for detecting gallstones due to its high sensitivity. However, CT scans can provide valuable information in complex cases, especially in older patients or those with uncertain presentations. The importance of appropriate imaging strategy becomes significant in guiding treatment decisions, such as the need for surgery or further interventions.
Managing Gallbladder Complications and Interventions
The conversation emphasizes the urgency in addressing gallbladder complications such as acute cholecystitis and sterile management protocols. The necessity for timely surgical intervention, especially within 24 hours of presentation, is underscored to minimize morbidity and prevent the progression of disease. Surgical strategies, including the use of cholecystostomy tubes for drainage in high-risk patients, are discussed as essential to control infection and relieve symptoms. Finally, the podcast concludes with practical advice for emergency physicians on recognizing gallbladder issues, diagnostic strategies, and when to call in surgical support.
Dr. Henry Schiller, Professor of Surgery, Liutenant Colonel in the US Army Reserve, and Mayo Clinic Teaching Hall of Fame inductee rejoins the show to talk about gallbladders. We review the distinction between the evaluation and management of cholelithiasis, choledocolithiasis, the role of different imaging modalities, and much more in this awesome chapter of the show - dont miss this!
Childs DD, Lalwani N, Craven T, Arif H, Morgan M, Anderson M, Fulcher A. A meta-analysis of the performance of ultrasound, hepatobiliary scintigraphy, CT and MRI in the diagnosis of acute cholecystitis. Abdom Radiol (NY). 2024 Feb;49(2):384-398. doi: 10.1007/s00261-023-04059-w. Epub 2023 Nov 20. PMID: 37982832.
de Oliveira GS, Torri GB, Gandolfi FE, Dias AB, Tse JR, Francisco MZ, Hochhegger B, Altmayer S. Computed tomography versus ultrasound for the diagnosis of acute cholecystitis: a systematic review and meta-analysis. Eur Radiol. 2024 Nov;34(11):6967-6979. doi: 10.1007/s00330-024-10783-8. Epub 2024 May 17. PMID: 38758253.
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