Laser Therapy Institute Podcast cover image

Laser Therapy Institute Podcast

REVIEW: Laser for Neurodegenerative Disease

Mar 14, 2022
They discuss photobioimodulation for neurodegeneration, explaining its mechanisms and therapeutic effects. They explore cellular mechanisms, regeneration, and intracellular signaling pathways. The complexity of neurodegenerative diseases and the role of heat shock proteins are also discussed. The therapeutic effects of laser therapy include preventing neuron atrophy and improving symptoms. Application and limitations of laser therapy are addressed.
37:56

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Quick takeaways

  • Photobiomodulation, also known as laser therapy, has shown potential as a therapeutic tool for neurodegenerative diseases by stimulating cellular mechanisms, enhancing neuroprotection, preventing cell death, and promoting repair processes.
  • Pharmacological drugs targeting specific signaling cascades have shown limited success in slowing the progression of neurodegenerative diseases, highlighting the need for alternative approaches like laser therapy that leverage cellular mechanisms and offer a comprehensive approach.

Deep dives

Photobiomodulation for Neurodegeneration

Photobiomodulation, also known as laser therapy, has shown potential as a therapeutic tool for neurodegenerative diseases such as dementia, Alzheimer's, Parkinson's, and more. By using safe and non-invasive light, photobiomodulation stimulates cellular mechanisms that decelerate disease progression and enhance neuroprotection. It stimulates mitochondrial activity, triggers signaling pathways, and activates stress response systems within cells. It prevents neuron atrophy and apoptosis, increases stem cell circulation, and restores dopamine production. Moreover, photobiomodulation influences an interconnected network of cellular signaling, produces neuroprotective and anti-inflammatory responses, and increases antioxidant capacity. It can also reduce the burden of amyloid plaques and pathology-dependent effects. While more research is needed to determine optimal settings and wavelengths for transcranial application, healthcare providers can benefit from existing protocols and guidance provided by Laser Therapy Institute.

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