They discuss photobioimodulation for neurodegeneration, explaining its mechanisms and therapeutic effects. They explore cellular mechanisms, regeneration, and intracellular signaling pathways. The complexity of neurodegenerative diseases and the role of heat shock proteins are also discussed. The therapeutic effects of laser therapy include preventing neuron atrophy and improving symptoms. Application and limitations of laser therapy are addressed.
Photobiomodulation, also known as laser therapy, has shown potential as a therapeutic tool for neurodegenerative diseases by stimulating cellular mechanisms, enhancing neuroprotection, preventing cell death, and promoting repair processes.
Pharmacological drugs targeting specific signaling cascades have shown limited success in slowing the progression of neurodegenerative diseases, highlighting the need for alternative approaches like laser therapy that leverage cellular mechanisms and offer a comprehensive approach.
Deep dives
Photobiomodulation for Neurodegeneration
Photobiomodulation, also known as laser therapy, has shown potential as a therapeutic tool for neurodegenerative diseases such as dementia, Alzheimer's, Parkinson's, and more. By using safe and non-invasive light, photobiomodulation stimulates cellular mechanisms that decelerate disease progression and enhance neuroprotection. It stimulates mitochondrial activity, triggers signaling pathways, and activates stress response systems within cells. It prevents neuron atrophy and apoptosis, increases stem cell circulation, and restores dopamine production. Moreover, photobiomodulation influences an interconnected network of cellular signaling, produces neuroprotective and anti-inflammatory responses, and increases antioxidant capacity. It can also reduce the burden of amyloid plaques and pathology-dependent effects. While more research is needed to determine optimal settings and wavelengths for transcranial application, healthcare providers can benefit from existing protocols and guidance provided by Laser Therapy Institute.
Challenges with Pharmacological Drugs
Pharmacological drugs targeting specific signaling cascades have shown limited success in slowing the progression of neurodegenerative diseases. Singularly targeting one pathway often fails because of the interconnectedness and complexity of these processes. Most drugs that are successful in animal studies do not yield the same results in humans. Therefore, relying solely on drug treatments may not be effective in combating neurodegenerative diseases.
Implications for Clinical Practice
Understanding the cellular mechanisms and therapeutic effects of photobiomodulation is crucial for healthcare providers. Although direct translation from animal studies to human practice is not possible, protocols and settings based on current research can be employed. Laser Therapy Institute offers support, protocols, practice coaching, and equipment guidance to healthcare providers interested in incorporating laser therapy into their practices. By leveraging this knowledge, practitioners have the opportunity to enhance patient outcomes and contribute to the fight against neurodegeneration.
Conclusion
Photobiomodulation shows promise as a non-invasive and safe therapeutic tool for neurodegenerative diseases. By stimulating cellular mechanisms and activating various pathways, it contributes to neuroprotection, prevents cell death, and promotes repair processes. While drug treatments often fall short of addressing the complex nature of neurodegeneration, laser therapy offers a comprehensive approach. Healthcare providers can benefit from the guidance provided by Laser Therapy Institute to effectively integrate laser therapy into their practices and positively impact patients' lives.
A 2020 review on light therapy mechanisms with neurodegenerative disease is the focus of Dr. Rountree and Kristi’s discussion today. Together they review what neurodegeneration is, what light and laser treatment looks like for neurodegeneration diseases, and the cellular mechanisms and the therapeutic effects we expect to see in relation to these mechanisms. Follow along for information on how and why laser therapy works. Dr. Rountree also has a few cautions and information for light and laser therapy clinics in regards to the use of photobiomodulation for neurodegenerative diseases.
We have begun live-streaming this podcast. Watch this episode on Facebook right here. See the next episode LIVE in two weeks!