The Science Behind Probiotics Enhancing B Vitamin Absorption

In this episode of Daily Value I cover recent research suggesting specific probiotic species may enhance the bioavailability of essential B-vitamins, offering insights into a [potentially] synergistic approach for optimizing metabolic and gut health.

Covered in the episode
- How some Lactobacillus species were shown to significantly increase the absorption of vitamins B1, B3, B5, and B12 in rodent models, despite these strains not being direct producers of B-vitamins.
- Proposed mechanisms, including alterations in gut pH and microbial cross-feeding dynamics, that facilitate enhanced vitamin uptake and influence overall nutrient absorption pathways.
- Contrary to the common belief that higher bacterial diversity is always favorable, the episode discusses how a targeted decrease in diversity may yield positive outcomes in terms of mucosal integrity and anti-inflammatory effects.

The findings discussed in this episode suggest potential therapeutic strategies for individuals with compromised gastrointestinal function or B-vitamin deficiencies. By combining high-quality B-vitamin supplementation with specific probiotic strains, there may be a pathway to more personalized and effective interventions. However, it’s crucial to consider individual variability, including baseline microbiota composition and genetic factors, when translating these findings to human populations.

https://pubs.rsc.org/en/content/articlelanding/2024/fo/d4fo01805b