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Out of Africa
- McNeil suggests that humanity's exodus from Africa was driven by the desire to escape the continent's diverse and challenging parasite populations.
- He points out that Africa has the most variety of human parasites and remains one of the most balanced ecosystems.
Ebbing and waning
- As societies become more complex, so does their relationship with microparasites.
- McNeil suggests that irrigation farming, while enabling societal growth, also created conditions for the spread of debilitating diseases like schistosomiasis.
Diseases of Civilization
- Viruses are "diseases of civilization" because they require large, dense populations to thrive.
- McNeil argues that the minimum population size to sustain a virus like measles is around half a million, coincidentally similar to the population of ancient Sumeria.