Today, we’re talking with The Gene Queen Sarah Morgan about … Unlocking the Choline Connection: A Key to Alzheimer's Puzzle in Women - Decoding Its Impact, Genetic Factors, and Vital Strategies for Optimal Brain Health.
Key Points
- Women may go into pregnancy choline deficient and have huge demand in pregnancy and lactation.
- In perimenopause. Estrogen levels decline. PEMT activity declines. Why? Estrogen is an inducer of PEMT activity. Low estrogen = Low choline production
- Memory declines, sleep worsens.
- We may increase the risk of Alzheimer’s over decades through choline deprivation.
- Key gene = PEMT (rs7946 and rs12325817)
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