Episode 59. Management of Systemic Mastocytosis with Dr. Daniel DeAngelo

In this episode, we discussed the management of systemic mastocytosis with Dr. Daniel DeAngelo from the Dana Farber Cancer Institute. Here are the key studies we discussed:

• Midostaurin https://www.nejm.org/doi/10.1056/NEJMoa1513098?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200www.ncbi.nlm.nih.gov
• Avapritinib
• EXLPORER study: https://www.nature.com/articles/s41591-021-01538-9
• PATHFINDER study: https://www.nature.com/articles/s41591-021-01539-8
• Bezuclastinib: APEX trial: https://ashpublications.org/blood/article/144/Supplement%201/659/530240/Apex-Part-1-Updated-Assessment-of-Bezuclastinib
• HSCT for Advanced SM: https://ascopubs.org/doi/10.1200/JCO.2014.55.2018