Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

Exploring Endogenous DMT with Rick Strassman, MD

Jan 3, 2024

Rick Strassman, MD, an adjunct associate professor at the University of New Mexico and pioneer in DMT research, shares fascinating insights on endogenous DMT. He discusses its production in humans and its connection to near-death experiences involving the pineal gland. Strassman highlights the personal nature of DMT experiences, emphasizing how individual backgrounds shape perceptions. He also explores the relationship between fear and the intensity of psychedelic experiences, and intriguingly links the spiritual with the neurological, questioning universal mystical experiences across cultures.

52:41

Creator website

Episode guests

Rick Strassman

AI Summary

AI Chapters

Episode notes

Podcast summary created with Snipd AI

Quick takeaways

Dr. Strassman highlights the importance of individual mental states and expectations in shaping the subjective nature of DMT experiences, indicating variability in outcomes.

Recent research challenges the assumption of the pineal gland's role in DMT production, suggesting that synthesis actually occurs in the visual cortex during extreme states.

Deep dives

Exploring Endogenous DMT

Endogenous DMT is a naturally occurring substance in the body that plays a significant role in altered states of consciousness. Dr. Rick Strassman discusses his hypothesis that there might be a connection between endogenous DMT production and experiences such as meditation and spiritual encounters. His early research focused on understanding the effects of DMT through controlled studies and examining how it correlates with conditions like schizophrenia. Strassman emphasizes that DMT's influence varies among individuals based on their mental state and expectations during the experience.

Intro

2min

Exploring DMT: Insights and Experiences

13min

Exploring Endogenous DMT and Near-Death Experiences

21min

Psychoactive Compounds and Perception

8min

Exploring Spirituality Through Biblical Prophecy and Psychedelics

2min

Understanding Shared Experiences in DMT Journeys

3min

Exploring DMT and Its Theological Connections

4min

In this episode of the Psychedelic Medicine Podcast, Rick Strassman, MD joins to discuss the topic of endogenous DMT. Dr. Strassman is adjunct associate professor of psychiatry at the University of New Mexico in Albuquerque and author of DMT: The Spirit Molecule and The Psychedelic Handbook. His DMT and psilocybin studies in the early 1990s initiated the renewal of human research with psychedelics in the U.S.

In this conversation, Dr. Strassman discusses the finer details of DMT, from endogenous production in humans and animals, to visionary experiences and theological implications. Dr. Strassman also covers the research that's been done regarding endogenous DMT, clarifying what we do and don’t know about the role of the pineal gland and how this might relate to what is reported during near-death experiences. He also discusses the personal and relational quality of psychedelic experiences induced by DMT, mentioning that unitive mystical experiences were actually rare in the trials he conducted, with more experiences having a personal quality, drawing upon the life experiences and interests of the participants. In closing, Dr. Strassman shares his thoughts on the origins of the visions that many report during DMT use.

In this episode you'll hear:

The overlap between psychedelic experiences and meditation techniques
The relationship between fear, self-awareness, and difficult DMT experiences
The placebo effect and psychedelic research
Dr. Strassman’s thoughts on non-hallucinogenic psychedelics
DMT as a possible treatment for strokes to prevent damage and speed recovery
Effects of microdosing in animals and humans

Quotes:

“I think the best term for these compounds is psychedelic, which means mind manifesting or mind disclosing, because only one of our fifty-five or so normal volunteers had what one might call a mystical unitive state. … Everybody basically had an experience that was totally dependent on them. It was not inherent in the drug.” [9:45]

“You could still speculate that to the extent that non-drug states resemble those brought on by giving DMT… that DMT plays a role in the production of those states. But the data aren't there yet. That's why we need more people doing this research.” [24:16]

“If psychedelics are super placebos and if we have a psychedelic drug in our brain, it's attempting to speculate that normally the placebo effect could be mediated by endogenous DMT.” [27:42]

“If you starve neurons of oxygen they start dying, but if you add DMT they survive much longer. So there seems to be some neuroprotective effect of DMT on ischemic damage to neurons, at least in the test tube.” [32:27]

Links:

Dr. Strassman’s website

The Psychedelic Handbook by Dr. Strassman

DMT: The Spirit Molecule by Dr. Strassman

DMT and the Soul of Prophecy: A New Science of Spiritual Revelation in the Hebrew Bible by Dr. Strassman

Dr. Strassman on Facebook Previous episode: Exploring DMT Entities with Matthew Johnson, PhD

Psychedelic Medicine Association

Porangui