Core IM | Internal Medicine Podcast #85 Dual Antiplatelet Therapy: 5 Pearls Segment
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Apr 7, 2021 AI Snips
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DAPT for ACS
- Consider dual antiplatelet therapy (DAPT) for acute coronary syndromes (ACS), regardless of cath lab or stent placement.
- DAPT benefits ACS patients by reducing thrombotic events, even without stents.
Stent Thrombosis vs. Restenosis
- DAPT post-PCI prevents stent thrombosis, a sudden clotting event.
- It doesn't prevent in-stent restenosis, a chronic cell proliferation.
Choosing P2Y12 Inhibitors
- Consider potency, bleeding risk, and cost when choosing a P2Y12 inhibitor.
- Clopidogrel is less potent but has lower bleeding risk than prasugrel or ticagrelor.