Cell & Gene: The Podcast
Lessons in Automation with Roswell Park Comprehensive Cancer Center's Christopher Choi, Ph.D.
Jan 2, 2025
Christopher Choi, Ph.D., is an expert in cell and gene therapy manufacturing and the Director of the GMP Facility at Roswell Park Comprehensive Cancer Center. In this discussion, he reveals plans for a new Cell and Gene Therapy Hub set to open in 2025, aimed at advancing cancer treatment. Choi emphasizes the critical role of automation in manufacturing and shares valuable advice for emerging biotech firms on quality management, project coordination, and the importance of a quality by design approach to improve market readiness.
14:49
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Quick takeaways
- The Roswell Park Cell and Gene Therapy Hub, opening in 2025, aims to facilitate the transition from research to clinical application for cancer therapies.
- Automation and digital technologies are essential for overcoming manufacturing challenges in cell therapies, ensuring safety and consistency for unique patient cells.
Deep dives
Overview of the Cell and Gene Therapy Hub
The Roswell Park Cell and Gene Therapy Hub in Buffalo, New York, is set to open in early 2025 and aims to become a significant player in cancer treatment. It is designed to bridge the gap known as the 'valley of death,' where preclinical research often fails to progress to clinical trials due to financial and operational challenges. This hub will provide the necessary infrastructure to translate scientific ideas into clinical applications, emphasizing the need for cell therapies to combat cancer more effectively. With a focus on collaboration, the hub aims to support both internal researchers and those from other institutions, positioning itself as a vital resource in cancer research and treatment.
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