
COVID-19 Vaccine Updates COVID-19 Vaccine Updates: Vaccine Safety
Nov 3, 2021
Kevin Winthrop, a Professor of Infectious Diseases and Epidemiology at Oregon Health and Science University, dives deep into the safety profiles of mRNA and adenoviral COVID-19 vaccines. He discusses their efficacy, addressing rare side effects and the crucial benefit-risk ratios. Winthrop emphasizes the importance of vaccination in minimizing severe cases, especially during peaks of the pandemic. His insights provide valuable information for anyone concerned about vaccine safety.
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mRNA Vaccines' Exceptional Benefit-Risk
- mRNA COVID-19 vaccines likely rank among the safest vaccines ever given widespread use and monitoring.
- Kevin Winthrop emphasizes the benefit-risk ratio strongly favors vaccination during the pandemic.
Expect Short-Lived Reactogenicity
- Reactogenicity (fatigue, myalgias, joint pain) is the most common vaccine side effect and is usually short-lived.
- These reactions are more common after the second dose and in younger people, and are not a sign to avoid vaccination.
Autoimmune Flares Are Rare And Manageable
- Early data do not show widespread flares of autoimmune disease after vaccination, with flare rates similar to baseline.
- Most flares that occur are manageable and not a reason to avoid vaccination for autoimmune patients.

