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In this episode of Psychedelic Therapy Frontiers, Dr. Steve Thayer and Dr. Reid Robison explore how psychedelic medicine might make one more psychologically flexible. They discuss what psychological or cognitive flexibility means, how it’s implicated in mental health, how psychedelics influence it, the concept of entropy applied to the brain, and much more.

(1:29) Strength and flexibility
(3:29) The REBUS model and entropic brain theory
(4:04) Neuroplasticity
(8:38) The transdiagnostic benefits of psychedelics
(9:28) Acceptance and Commitment Therapy (ACT)
(11:14) Mindfulness and equanimity
(17:14) Resistance leads to suffering
(19:20) Living Untethered, by Michael A. Singer
(21:48) Psychedelics and psychosis
(23:30) Risks of ego inflation and the importance of set and setting
(25:55) Ketamine dreams
(28:37) Ego dissolution and the default mode network
(32:10) Psychedelics won't do the work for you. They're tools.

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