The Brian Lehrer Show FDA Panel's "Misinformation" on Antidepressant Use in Pregnancy
Aug 5, 2025
Lauren Osborne, M.D., is the vice chair of Clinical Research at Weill Cornell Medicine and a leader in reproductive psychiatry. She discusses the recent FDA panel's controversial stance on SSRIs during pregnancy, highlighting the backlash from medical professionals. Osborne emphasizes the need for evidence-based treatment to improve maternal mental health amid rising distrust in pharmaceutical practices. Personal stories reveal the emotional struggle pregnant women face in managing their mental health, showcasing the complexity of navigating treatment options.
AI Snips
Chapters
Transcript
Episode notes
Treating Depression in Pregnancy
- For mild to moderate depression during pregnancy, try non-drug treatments like therapy or prenatal yoga first.
- Use SSRIs for moderate to severe cases or past severe history to protect maternal and fetal health.
SSRIs Not Proven To Cause Autism
- Early studies linking SSRIs to autism used inappropriate comparison groups without depression, skewing results.
- Recent research shows no credible evidence that SSRIs cause autism or major birth defects.
Depression Risks Beyond Medication
- Maternal depression itself increases risks of autism, preterm birth, and low birth weight.
- Mental illness impacts prenatal care and substance use, affecting child outcomes independently of medication.