Pascal Touchon 🇫🇷 | Cell Therapy, Jeito, Kymriah | E49

Pascal Touchon unpacks why the next CAR-T innovations, including allogeneic and in vivo therapies, are going to be so exciting.

The cell therapy master outlines his central role in bringing two first‑in‑class cell therapies to patients: Kymriah, the first approved CAR‑T, and Ebvallo, the first approved allogeneic T‑cell therapy.

We also explore his new position as an operating partner at Jeito and how we need to work harder to find Europe’s hidden biotech gems.

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⭐️ ABOUT THE SPEAKER

With many years of experience in big pharma, Pascal had top-level positions at Novartis Oncology. He later served as CEO, and most recently Chairman, of Atara Biotherapeutics. Alongside his Jeito role, he sits on the boards of companies including Ipsen, Medincell, Catalym, Xylocor and CDR-Life.

🔗 LINKS MENTIONED

• Jeito’s website: https://www.jeito.life/en/home/
• Stefano Portolano, Azafaros | Rare Diseases, Small Molecules Revival | E40: https://www.youtube.com/watch?v=gdaPW7xg_qk
• Otello Stampacchia, Omega Funds 🇮🇹 | Competition, Boston & Pasta | E18: https://flot.bio/episode/otello-stampacchia-omega-funds/
• Fabrice Chouraqui, Pharming 🇳🇱 | Transgenic Rabbits, Rare Diseases | E43: https://flot.bio/episode/fabrice-chouraqui-pharming-transgenic-rabbit/
• Laurent Levy, Nanobiotix 🇫🇷 | Nanoparticles, Radiotherapy | E45: https://flot.bio/episode/laurent-levy-nanobiotix-nanoparticles-radiotherapy/
• Marc de Garidel, Abivax | How to make two Billion-dollar exits (“smoothly”) | E09: https://flot.bio/episode/marc-de-garidel-abivax-exit/

📜 TRANSCRIPT

Read the full transcript here: https://flot.bio/episode/pascal-touchon-jeito/

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Flot.bio is a show to watch the best Europeans in biotech to help you grow. Hosted by Philip Hemme. 25k monthly views. Free.

⏰ TIMESTAMPS

• [00:00:00] Intro
• [00:02:40] The rise of Kymriah and Ebvallo
• [00:05:40] CAR-T: crazy innovations and valuations
• [00:20:35] Solid tumor challenges
• [00:23:18] Cell therapy manufacturing and in vivo CAR-T
• [00:31:38] Catching the innovation wave at Jeito Capital
• [00:39:29] VC models and European biotech gems
• [00:52:51] Biotech without borders
• [01:05:49] France’s rising pharma stars
• [01:08:30] Quick-fire questions