Notes:
NP03, a Microdose Lithium Formulation, Blunts Early Amyloid Post-Plaque Neuropathology in McGill-R-Thy1-APP Alzheimer-Like Transgenic Rats: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad190862
Can lithium halt progression of Alzheimer's disease?: https://www.sciencedaily.com/releases/2020/01/200125090727.htm
Microdose Lithium Treatment Reduced Inflammatory Factors and Neurodegeneration in Organotypic Hippocampal Culture of Old SAMP-8 Mice: https://pubmed.ncbi.nlm.nih.gov/32642922/
Low-dose Lithium treatment for agitation and psychosis in Alzheimer’s disease and Frontotemporal dementia: A case series: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322244/
Lithium Orotate Stops Alzheimers: https://beforeitsnews.com/eu/2012/12/lithium-orotate-stops-alzheimers-2488838.html?utm_source=dlvr.it&utm_medium=twitter
Lithium Orotate Risks: https://www.superfoodly.com/lithium-orotate/
On the Physiological function of lithium from a psychiatric viewpoint:
https://pubmed.ncbi.nlm.nih.gov/11601880/
The Faces of Mania: The Legacy of Athanasios Koukopoulos:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405619/
The History of Lithium Therapy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712976/
History of the Introduction of Lithium into Medicine and Psychiatry:
http://inhn.org/books/books/johan-schioldann-history-of-the-introduction-of-lithium-into-medicine-and-psychiatry-birth-of-modern-psychopharmacology-1949-reviewed-by-barry-blackwell.html
Lithium increases N-acetyl-aspartate in the human brain:
https://pubmed.ncbi.nlm.nih.gov/10913502/
N-acetylaspartate concentration in corpus callosum is positively correlated with intelligence in adolescents: https://pubmed.ncbi.nlm.nih.gov/21983183/
A Role in Neuroprotection against N-methyl-D-aspartate receptor-mediated excitotoxicity https://www.sciencedirect.com/science/article/pii/S0014579303001674
Neuroplasticity via glycogen synthase kinase-3beta, beta-catenin, and neurotrophin cascades: https://pubmed.ncbi.nlm.nih.gov/19423950/
Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?: https://pubmed.ncbi.nlm.nih.gov/10509176/
Lithium in drinking water and the incidences of crimes, suicides, and arrests related to drug addictions: https://pubmed.ncbi.nlm.nih.gov/1699579/
Lithium orotate in the treatment of alcoholism and related conditions:
https://pubmed.ncbi.nlm.nih.gov/3718672/
Reduced Serotonin Reuptake Transporter (SERT) Function Causes Insulin Resistance and Hepatic Steatosis Independent of Food Intake:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297606/
Medications for Mental Health Treatment: https://dualdiagnosis.org/mental-health-and-addiction/medications/
Long-Term Lithium Treatment Causes Serotonin Receptor Down-Regulation via Serotonergic Presynapses in Rat Brain:
https://www.karger.com/Article/PDF/118292
Mutation links bipolar disorder to mitochondrial disease:
https://www.eurekalert.org/pub_releases/2018-06/r-mlb060818.php
Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder: https://www.nature.com/articles/s41380-018-0074-9
Dietary amino acids and brain function: https://pubmed.ncbi.nlm.nih.gov/7903674/
Research explains lithium’s dual anti-manic/ anti-depressive effect:
https://news.wisc.edu/research-explains-lithiums-dual-anti-manic-anti-depressive-effect/
Orotic Acid: Why it is Important to Understand Its Role in Metabolism:
https://www.omicsonline.org/open-access/orotic-acid-why-it-is-important-to-understand-its-role-in-metabolism-2168-9652-1000e157.php?aid=90853
Nutritional therapies for mental disorders:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248201/
Products:
Lithium Orotate: https://amzn.to/2XKCgVd
Lithia Water(Lithium Chloride): https://amzn.to/33HBufz
Ionic Lithium (Lithium Chloride): https://amzn.to/33JtFWz
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