
American Thought Leaders New Evidence Shows SSRI Antidepressants Can Cause Permanent Harm to Sexual Function | Dr. Irwin Goldstein
Nov 1, 2025
Dr. Irwin Goldstein, a leading sexual health physician and director of San Diego Sexual Medicine, sheds light on the troubling phenomenon of post-SSRI sexual dysfunction (PSSD). He reveals that SSRIs can cause lasting sexual issues like erectile dysfunction and loss of libido, even after treatment stops. Goldstein discusses the lack of awareness among clinicians about PSSD risks and the potential for permanent damage. He emphasizes the need for informed consent and further research into genetic predispositions, challenging the belief that these side effects are purely psychological.
AI Snips
Chapters
Transcript
Episode notes
SSRIs Can Produce Lasting Sexual Harm
- SSRIs raise serotonin, which inhibits sexual function and can cause dysfunction while taking the drug.
- Dr. Irwin Goldstein reports many patients do not recover sexual function after stopping SSRIs, contradicting common teaching.
Young Patients With Lifelong Damage
- Goldstein describes patients given SSRIs as young as 11 who will never experience what most consider a normal sexual life.
- He emphasizes these are FDA-approved medicines, not poisons, complicating consent and prescribing.
Warn And Weigh Risks Before Prescribing
- Inform patients about sexual risks and weigh situational need before prescribing SSRIs, especially to minors.
- Consider counseling for situational sadness rather than immediately prescribing serotonergic drugs.
