Joint Action

Can weight loss shots reduce knee pain? Exploring Semaglutide's impact on osteoarthritis with Prof. Henning Bliddal

Dec 8, 2024

In this discussion, Professor Henning Bliddal, a renowned researcher in osteoarthritis treatment from Denmark, shares groundbreaking insights on Semaglutide. Originally aimed at weight loss, this drug has shown remarkable ability to alleviate knee pain for osteoarthritis sufferers. Henning reveals how weight loss reduces joint pressure, leading to improved mobility. He discusses the impressive results from clinical trials, practical tips for staying active, and ongoing research needed to ensure long-term benefits for patients.

39:22

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Henning Bliddal

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Quick takeaways

Semaglutide significantly reduces pain and improves mobility in individuals with knee osteoarthritis through effective weight loss management.

The sustainability of weight loss post-treatment with Semaglutide raises concerns, emphasizing the need for long-term strategies to maintain benefits.

Deep dives

The Impact of Weight Loss on Osteoarthritis

Weight loss has been shown to significantly benefit individuals with osteoarthritis, particularly in the knees and hands. A recent trial demonstrated that a drug facilitating weight loss led to marked improvements in pain and function among participants with symptomatic knee osteoarthritis. The reduction in weight decreases the load exerted on the joints, improving mobility and decreasing discomfort. This relationship underscores the importance of weight management as a non-surgical intervention to alleviate osteoarthritis symptoms.

Intro

2min

Exploring Weight Loss Drugs and Osteoarthritis: A Call for Questions

3min

Rehabilitation Insights: A Journey Beyond Osteoarthritis

5min

Innovative Approaches to Weight Loss in Osteoarthritis

24min

Exploring Weight Loss Treatments and Osteoarthritis

4min

Exploring the Impact of Semaglutide on Weight Loss and Knee Osteoarthritis

5min

This week on the Joint Action podcast, we’re joined by Professor Henning Bliddal, a leading researcher and Director at the Parker Institute in Denmark. Henning Bliddal has spent his career helping people with osteoarthritis live better lives.

In this episode, we talk about a breakthrough study using a medication called Semaglutide. This drug, originally made to help with weight loss, has shown amazing results in easing pain and improving movement for people with knee osteoarthritis. Henning explains how weight loss can take the pressure off your joints and why this is so important for managing knee osteoarthritis.

We cover:

How Semaglutide works and why it helps with knee pain.
The impressive results of the study, including big improvements in pain and function.
Practical tips for staying active and managing weight to reduce joint stress.
What we still need to learn about maintaining long-term benefits.

If you’re curious about the latest in osteoarthritis research and want practical tips for managing symptoms, join us on this week's episode.

RESOURCES

Have a question about osteoarthritis that you'd like answered? Send your question to osteoarthritis.research@sydney.edu.au by 16th December 2024 for a chance to have it featured in the final episode for 2024.

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