

EAST/AAST/AAST-AMC: SCC Review Series - Shock
Jun 6, 2025
In this engaging discussion, Dr. Joseph Cuschieri, a seasoned surgical expert, shares his insights alongside critical care fellows Dr. Gerald Wang and Dr. Kirea Mazzolini. They dive deep into the intricate pathophysiology of shock, covering its various types like septic and hemorrhagic shock. The trio emphasizes evidence-based resuscitation strategies and the strategic use of vasopressors. Listeners can also expect real case studies that highlight the dynamic decision-making needed in critical care environments, making the complex topic accessible and relatable.
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Shock Pathophysiology Basics
- Shock is acute circulatory failure causing inadequate oxygen delivery.
- This leads to metabolic failure, lactic acidosis, and multi-organ dysfunction.
Cautious Fluid & Vasopressor Use
- Assess intravascular volume cautiously to avoid over-resuscitation.
- Use dynamic parameters and early vasopressors if shock persists after fluids.
One-Hour Sepsis Bundle
- Within one hour in sepsis, obtain lactate, blood cultures, and give broad-spectrum antibiotics.
- Administer rapid crystalloid fluids and start vasopressors as needed to maintain MAP >65.