377. CardioOncology: Multi-modality Imaging in Cardio-Oncology with Dr. Nausheen Akhter
Jun 24, 2024
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Dr. Nausheen Akhter discusses multi-modality imaging in cardio-oncology. Topics include monitoring LVEF with nuclear imaging, using MRI for cardiotoxic therapy surveillance, identifying coronary disease with CT, and diagnosing cardiac amyloidosis. The episode emphasizes the role of imaging in managing cardiotoxicity during cancer treatment and long-term surveillance strategies.
Utilization of advanced imaging modalities like echocardiography and cardiac MRI is crucial for monitoring patients on cardiotoxic therapies and long-term surveillance.
Imaging plays a key role in diagnosing cardiac amyloidosis and identifying coronary disease, emphasizing the importance of comprehensive cardiovascular assessment in cardio-oncology.
Deep dives
Importance of Cardiac Imaging in Cardioncology
Cardiac imaging plays a crucial role in cardioncology by providing essential insights into monitoring and managing cardiovascular health in cancer patients. With the use of imaging modalities like echocardiography and MRI, healthcare professionals can assess cardiac function, detect early signs of cardiotoxicity from cancer treatments, and tailor interventions to minimize adverse cardiovascular effects. Imaging not only helps in baseline assessments but also guides ongoing surveillance and risk stratification during and after cancer therapy, ensuring optimal patient care.
Monitoring and Surveillance Strategies for Cardiotoxicity
In patients undergoing cardiotoxic cancer therapies like anthracyclines and radiation, regular monitoring and surveillance are essential to detect and manage potential cardiovascular complications. Baseline echocardiograms, including measures like LVEF and global longitudinal strain, help in assessing cardiac function and predicting adverse events. Furthermore, advanced imaging techniques such as cardiac MRI offer detailed tissue characterization and aid in risk assessment for conditions like cardiac amyloidosis. Close surveillance, guided by imaging findings, allows for timely intervention and personalized care.
Future Perspectives and Challenges in Cardioncology Imaging
The evolving landscape of cardi oncology imaging presents exciting opportunities and challenges for improving patient outcomes. Advanced imaging technologies, such as strain analysis and MRI, offer valuable prognostic information and guide treatment decisions in cardioncology. As researchers explore the utility of imaging in emerging areas like immune checkpoint inhibitor-related myocarditis and atherosclerosis, continuous innovation in imaging protocols and risk stratification approaches is crucial. Embracing these technological advancements and enhancing collaboration among cardiologists, oncologists, and imaging specialists will drive further advancements in cardioncology care.
CardioNerds Co-Founder Dr. Daniel Ambinder, Series Co-Chair Dr. Giselle Suero Abreu (FIT at MGH), and Episode Lead Dr. Iva Minga (FIT at the University of Chicago) discuss the use of multi-modality cardiovascular imaging in cardio-oncology with expert faculty Dr. Nausheen Akhter (Northwestern University). Show notes were drafted by Dr. Sukriti Banthiya and episode audio was edited by CardioNerds Intern and student Dr. Diane Masket.
They use illustrative cases to discuss:
Recommendations on the use of multimodality imaging, including advanced echocardiographic techniques and cardiac MRI, in patients receiving cardiotoxic therapies and long-term surveillance.
Role of nuclear imaging (MUGA scan) in monitoring left ventricular ejection fraction.
Use of computed tomography to identify and/or monitor coronary disease.
Imaging diagnosis of cardiac amyloidosis.
This episode is supported by a grant from Pfizer Inc.
This CardioNerds Cardio-Oncology series is a multi-institutional collaboration made possible by contributions of stellar fellow leads and expert faculty from several programs, led by series co-chairs, Dr. Giselle Suero Abreu, Dr. Dinu Balanescu, and Dr. Teodora Donisan.
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References - Multi-modality Imaging in Cardio-Oncology
Baldassarre L, Ganatra S, Lopez-Mattei J, et al. Advances in Multimodality Imaging in Cardio-Oncology. J Am Coll Cardiol. 2022 Oct, 80 (16) 1560–1578.
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