Mechanistic Basis for Photobiomodulation Therapy of Neuropathic Pain

This podcast episode discusses the research and protocols for treating neuropathic pain using laser therapy. The hosts explain that laser therapy is a noninvasive way to deliver light energy to tissues and stimulate pain reduction and repair. They highlight the importance of using the right settings on the laser and treating patients often enough. The episode references a study that used different intensities of near-infrared light to study the effects on nerve cells. The researchers found that low irradiance can decrease pain response and alter chronic inflammation, while higher irradiance can suppress conduction velocity and block pain transmission. The hosts recommend a combination therapy approach, starting with high irradiance to block pain transmission, followed by a series of low irradiance treatments to stimulate repair. They emphasize the importance of having a high-power laser with a larger spot size to cover the entire length of the nerve. They also mention the significance of wavelength and the benefits of multi-wavelength devices. They conclude by offering their own LTI neuropathy protocols and encouraging clinicians to seek assistance and training for optimal results.