

TWiV 1243: Capitalism, COVID, and cancer
Aug 10, 2025
The conversation dives into the implications of a controversial executive order impacting scientific funding, raising alarms about oversight and bias. mRNA vaccines are defended as lifesavers, countering misinformation surrounding their efficacy. Innovative HIV treatment lenacapavir is discussed, showcasing its potential in patient care. The podcast also reveals how COVID-19 may reactivate dormant cancer cells, posing risks for survivors. Humorous segments blend with serious discussions, making for an engaging exploration of science and health.
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Political Oversight Of Grants Threatened
- The executive order forces political review of federal grants and injects ideology into funding decisions.
- Alan Dove warns this will delay awards, harm science, and cost jobs and economic activity.
Protect Vaccination Gains
- Do not accept HHS's rollback of mRNA vaccine support given their proven lives-saved record.
- Listen to experts like Jennifer Nuzzo and continue vaccination to prevent severe COVID outcomes.
Capsid Is A Stable HIV Target
- Targeting HIV's capsid attacks a highly conserved internal structure with limited room for escape.
- Alan Dove explains this makes capsid inhibitors like lenacapavir a robust antiviral strategy.