
Ep. 592 Comparing Thermal Ablation Techniques for Liver Lesions with Dr. Jason Hoffmann
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Nov 25, 2025 Dr. Jason Hoffman, an interventional radiologist at NYU Langone, dives deep into microwave ablation for liver lesions. He stresses the importance of educating patients and collaborating within multidisciplinary teams. Hoffman compares the benefits of microwave ablation to traditional methods and shares insights on patient selection and ideal lesion characteristics. The discussion also covers innovative technology from Varian and how AI could shape the future of the field. His expertise provides a compelling view on advancing interventional oncology practices.
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Microwave Ablation Has Matured
- Microwave ablation has evolved into a more powerful, reliable option compared with older RF technology.
- Recent improvements address prior concerns about unpredictable, non-spherical ablation zones.
Building An IO Practice From The Ground Up
- Jason built the Long Island IO practice after moving from Penn and faced early challenges proving value.
- He grew the service, now with seven IRs, through outreach, teaching, and persistence.
Prefer Ablation For Small, Limited Mets
- Prioritize ablation for small, limited metastatic liver lesions, especially colorectal mets under ~3 cm.
- Discuss tumor biology and multidisciplinary context before treating to set realistic expectations.
