Short Wave

Synthetic Cells: The Next Bioengineering Frontier

20 snips
Oct 13, 2025
Drew Endy, a leading engineer and synthetic biology researcher at Stanford University, discusses the quest to build synthetic cells from the bottom up. He explains how visualizing a cell as a building helps comprehend its functions. The conversation delves into the historical and engineering approaches that have made this possible. Endy highlights the freedom of designing synthetic cells without lineage constraints and emphasizes their potential to revolutionize bioengineering and sustainability. It's an intriguing exploration of life's fundamental building blocks!
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INSIGHT

Cells Are Complex And Poorly Understood

  • Cells are fundamental yet not fully understood at molecular level.
  • Biology still lacks a complete picture of how a living cell works.
INSIGHT

A Building-Sized Cell Is Crowded And Fast

  • Scaling a cell to building size reveals crowded, fast-moving molecular activity.
  • Ribosomes become person-sized and proteins move across the cell in seconds.
ANECDOTE

Building A Cell Like Stocking A Bookstore

  • Kate compares building a synthetic cell to filling a bookstore one shelf at a time.
  • She emphasizes knowing what parts go where so we can predict behavior.
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