Welcome back to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain dive into the world of diffused large B-cell lymphoma with special guest Dr. Carla Casulo from the Wilmot Cancer Institute in Rochester, New York.

Key Points Covered:
•⁠ ⁠Understanding the importance of accurate diagnosis through excisional biopsy in diffused large B-cell lymphoma.
•⁠ ⁠Exploring the significance of cell of origin in guiding treatment decisions.
•⁠ ⁠Initial treatment approaches for stage 1 and 2 disease, including the use of Polatuzumab based on the POLARIX trial.
•⁠ ⁠Treatment options for relapsed or refractory disease, including CAR-T therapy, BiTE therapy, and anti-CD19 antibody agents.
•⁠ ⁠Managing toxicities associated with different treatment regimens, such as cytopenias, infections, and neurotoxicity.

Join us as we unravel the complexities of diffused large B-cell lymphoma and discuss the latest advancements in treatment options with Dr. Carla Casulo. Stay informed and up to date with the Oncology Brothers podcast!

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How to treat Diffuse Large B-Cell Lymphoma (DLBCL) - Dr. Carla Casulo