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Published in 1962, 'One Flew Over the Cuckoo's Nest' is a seminal novel by Ken Kesey that delves into the dehumanizing effects of institutionalization and the struggle for individuality. The story, narrated by Chief Bromden, a half-Indian patient, takes place in an Oregon psychiatric hospital where the strict and oppressive regime of Nurse Mildred Ratched is challenged by the arrival of Randle P. McMurphy, a charismatic and rebellious patient. The novel explores the boundaries between sanity and madness, conformity and rebellion, and questions the power dynamics within institutions. It became a symbol of countercultural resistance and has had a significant impact on discussions surrounding mental health and societal treatment of the mentally ill.