The Joe Rogan Experience #2338 - Beth Shapiro
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Jun 17, 2025 
Beth Shapiro, an evolutionary molecular biologist and Chief Science Officer at Colossal Biosciences, dives into the cutting-edge world of ancient DNA and genetic innovation. She shares her hilarious misadventures in Siberia, facing mosquitoes and helicopter woes while uncovering secrets of human evolution. The discussion touches on ethical dilemmas around de-extinction and challenges in wildlife management. With captivating tales of mammoths and reindeer, Beth makes complex science accessible and highlights the need for diverse voices in research.
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Early DNA Contamination Issues
- Early ancient DNA research was plagued by contamination, including dinosaur DNA claims that turned out to be chicken DNA.
- This highlights the need for clean labs and improved techniques in paleogenomics.
Experiencing Dire Wolves
- Joe Rogan described his visit to see live dire wolves, noting their physical size and intense gaze.
- Beth Shapiro recounted witnessing Khaleesi's birth, emphasizing the emotional impact and wonder of de-extinction.
Teach Multiple Perspectives
- Teaching students to argue from multiple perspectives fosters critical thinking and understanding of complex conservation issues.
- This approach shifts opinions from initial enthusiasm to nuanced viewpoints about species reintroduction.
