
Mad Money w/ Jim Cramer Mad Money w/ Jim Cramer 11/21/25
14 snips
Nov 22, 2025 Sir Pascal Soriot, CEO of AstraZeneca, shares insights on the company’s ambitious $2 billion investment in U.S. manufacturing. He discusses job creation in Maryland and the expected impact on local communities. Soriot also delves into AstraZeneca’s oncology advancements, highlighting successes in breast cancer treatment. The conversation touches on strategic clinical developments and the implications of U.S. health policy on pricing. Jim Cramer provides valuable market insights, including how to spot market bottoms and harnessing trading intuition.
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Holiday Rally Dynamics Have Changed
- Machines now drive market moves and ignore human holiday patterns.
- That means expected seasonal rallies can fail as algo trading dominates.
Watch Retail And Housing To Gauge Rate Cuts
- Use weak retail and housing data as justification for Fed rate cuts.
- Watch retail sales and pending home sales for clues about December easing.
Positioning Ahead Of Hardware Earnings
- Consider owning Dell ahead of its quarter despite worries about semiconductor costs.
- Avoid HP, which Jim expects to be hostage to commodity swings.



